abiotrophy

/ˌeɪbaɪˈɑtrəfi/
noun
  1. The loss of function or degeneration of cells or tissues without an obvious external cause; often used in medical contexts for certain inherited diseases.
    • Abiotrophy of the nervous system can cause progressive muscle weakness.
    • Veterinarians identified a form of cerebellar abiotrophy in the young dog.
    • The patient was diagnosed with retinal abiotrophy, leading to gradual vision loss.
Synonyms
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