apoenzyme

/ˌæpoʊˈɛnzaɪm/
noun
  1. The protein part of an enzyme that requires a cofactor (such as a vitamin or metal ion) to become active.
    • Without its cofactor, the apoenzyme cannot catalyze any reaction.
    • The scientist isolated the apoenzyme and then added the necessary metal ion.
    • In the lab, students learned how an apoenzyme combines with a coenzyme to form a complete enzyme.
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