chancre

/ˈʃæŋkər/
noun
  1. A painless sore that appears on the skin or mucous membranes, usually as the first sign of syphilis.
    • The doctor identified a chancre on the patient's lip as a symptom of the infection.
    • Without treatment, a chancre will heal on its own, but the disease remains in the body.
    • Early detection of a chancre can help prevent the spread of syphilis to others.
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