derange

/dɪˈreɪndʒ/
verb
  1. To make someone insane or mentally disturbed.
    • The trauma of the accident seemed to derange his mind.
    • The horror movie was so disturbing it threatened to derange her.
    • Years of isolation can derange even the strongest person.
  2. To throw something into disorder or confusion.
    • The sudden change in schedule deranged our entire routine.
    • A power outage deranged the computer system's operations.
    • The unexpected guest deranged the careful seating arrangement.
Antonyms
What does "derange" mean? | whatsthatwordmean | whatsthatwordmean