irritation

/ˌɪr.ɪˈteɪ.ʃən/
noun
  1. The feeling of being annoyed or angry.
    • He tried to hide his irritation when the meeting ran late.
    • She felt a flash of irritation at his rude comment.
    • The constant noise from the street was a source of irritation for the family.
  2. A sore, red, or uncomfortable condition on a part of the body.
    • If the irritation persists, you should see a doctor.
    • The cream helped reduce the skin irritation from the bug bite.
    • Eye irritation can be caused by smoke or dust.