karyolysis

/ˌkɛriˈɑləsɪs/
noun
  1. The breakdown and dissolution of a cell's nucleus, especially during cell death.
    • Under the microscope, karyolysis was visible in the damaged tissue.
    • The pathologist noted karyolysis as a sign of necrosis in the sample.
    • Karyolysis occurs when enzymes break down the nuclear material after a cell dies.
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