missense

/ˈmɪsˌsɛns/
noun
  1. A type of genetic mutation where a single change in DNA causes one amino acid in a protein to be replaced by a different amino acid, which can affect the protein's function.
    • The scientist studied a missense mutation in the gene that caused the protein to malfunction.
    • The lab report identified a missense change that altered the shape of the enzyme.
    • Some diseases are linked to a single missense error in a person's DNA.
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