myelofibrosis

/ˌmaɪəloʊfaɪˈbroʊsɪs/
noun
  1. A rare bone marrow disorder in which the marrow is replaced by scar tissue, leading to problems with blood cell production.
    • The patient was diagnosed with myelofibrosis after experiencing severe fatigue and weight loss.
    • Doctors monitor myelofibrosis closely because it can sometimes turn into a more serious form of leukemia.
    • Myelofibrosis can cause an enlarged spleen because the body tries to make blood cells in other organs.