pachyderma
/ˌpækɪˈdɜrmə/
noun
- Abnormal thickening of the skin, often as a symptom of a medical condition.
- The dermatologist explained that pachyderma is different from normal calluses.
- The patient's pachyderma was a sign of a rare genetic disorder.
- Chronic lymphedema can lead to pachyderma in the affected limbs.