penetrance

/ˈpɛnɪtrəns/
noun
  1. The frequency or likelihood with which a genetic trait or condition is expressed in individuals who carry the associated gene.
    • Scientists studied the penetrance of the gene to understand why some people show symptoms and others do not.
    • Low penetrance can make it difficult to predict whether a person will actually develop a genetic disorder.
    • The penetrance of the BRCA1 mutation is high, meaning most carriers develop breast cancer.
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