penicillinase

/ˌpɛnɪˈsɪlɪneɪz/
noun
  1. An enzyme produced by some bacteria that breaks down penicillin and makes it ineffective.
    • The bacteria produced penicillinase, which destroyed the antibiotic before it could work.
    • Penicillinase is one reason some infections are hard to treat with common antibiotics.
    • Scientists developed drugs that block penicillinase to help fight resistant infections.
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