pestiferousness

/pɛˈstɪfərəsnəs/
noun
  1. The quality of being troublesome, annoying, or harmful.
    • The pestiferousness of the constant construction noise made it hard to concentrate.
    • The pestiferousness of the computer virus was clear when it crashed the entire network.
    • Gardeners complain about the pestiferousness of invasive species.