proband

/ˈproʊbænd/
noun
  1. The first person in a family to be identified with a genetic disorder or trait, used as a starting point for studying inheritance patterns.
    • In genetic studies, the proband is often the person who brings the family to the attention of doctors.
    • Researchers traced the family history back to the proband to understand how the disease spread.
    • The proband was a 12-year-old boy with a rare eye condition.
Synonyms
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