systemic

/sɪˈstɛmɪk/
adjective
  1. Relating to or affecting an entire system, not just a single part.
    • The doctor said the infection had become systemic and was affecting her whole body.
    • The company's problems were systemic, not just due to one bad manager.
    • Racism is a systemic issue that requires changes in laws and institutions.
Antonyms