variolization

/ˌvɛriəlaɪˈzeɪʃən/
noun
  1. The historical practice of deliberately infecting a person with a mild form of smallpox to produce immunity against the more severe disease.
    • Before vaccination was developed, variolization was a risky but sometimes effective way to prevent smallpox.
    • Historians note that variolization was practiced in parts of Asia and Africa long before it reached Europe.
    • The doctor explained that variolization involved transferring material from a smallpox pustule to a healthy person.
Synonyms
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