vicissitude
/vɪˈsɪsɪtud/
noun
- A change of circumstances or fortune, typically one that is unwelcome or difficult.
- The vicissitudes of the stock market made investors nervous.
- The family endured the vicissitudes of war and displacement.
- Her career had many vicissitudes, from sudden fame to years of struggle.
- The quality of being changeable; variability.
- The novel explores the vicissitude of human emotions over a lifetime.
- The vicissitude of the weather in spring makes it hard to plan outdoor events.
- He was tired of the vicissitude of city life and longed for stability.
Synonyms